Shanghai, Hong Kong and South Korea declined. Tokyo advanced. Oil prices were little changed, staying below $100 per barrel.
Wall Street tumbled Tuesday after Walmart warned inflation that has spiked to a four-decade high of 9.1% is hurting American consumer spending.
The Fed on Wednesday is expected to announce a rate hike of up to three-quarters of a percentage point, triple its usual margin. That would match a similar increase last month, the U.S. central bank's biggest in 28 years.
Investors worry aggressive action against inflation by the Fed and central banks in Europe and Asia might derail global economic growth.
“The main risk at this stage is in fact an inflation ‘overkill’ with monetary tightening too abrupt, unnecessarily pushing up the unemployment rate,” said Thomas Costerg of Pictet Wealth Management in a report. Thomas said most economic indicators and lower commodity prices already point to slower inflation ahead.
The Shanghai Composite Index lost 0.1% to 3,273.32 while Tokyo's Nikkei 225 advanced 0.1% to 27,692.89. The Hang Seng in Hong Kong sank 1.5% to 20,598.58.
The Kospi in Seoul retreated 0.6% to 2,398.48 and Sydney's S&P-ASX 200 shed 0.1% to 6,798.20.
New Zealand advanced while Southeast Asian markets declined.
On Wall Street, the benchmark S&P 500 index fell 1.2% to 3,921.05. The Dow Jones Industrial Average dropped 0.7% to 31,761.54. The Nasdaq composite closed 1.9% lower at 11,562.57.
Walmart slumped 7.6% after the retail giant cut its profit outlook for the second quarter and the full year late Tuesday. It said rising prices for food and gasoline are forcing shoppers to cut back on more profitable discretionary items, particularly clothing.
The retailer's profit warning in the middle of the quarter is rare and raised worries about how the highest inflation in 40 years is affecting the entire retail sector.
Other major chains also fell. Target dropped 3.6%, Macy’s slid 7.2% and Kohl’s fell 9.1%.
Tech stocks retreated. Microsoft fell 2.7%, Amazon slid 5.2% and Facebook owner Meta Platforms dropped 4.5%.
General Motors fell 3.4% after its second-quarter profit fell 40% from a year ago. U.S. sales fell 15% after shortages of processor chips and other components left the company unable to deliver 95,000 vehicles during the quarter.
In energy markets, benchmark U.S. crude rose 30 cents to $95.28 per barrel in electronic trading on the New York Mercantile Exchange. The contract fell $1.72 on Tuesday to $94.98. Brent crude, the price basis for international oils, added 5 cents to $99.51 per barrel in London.
The dollar rose to 136.97 yen from Tuesday's 136.00 yen. The euro gained to $1.0145 from $1.0120.
